| Rank | Name | Sacks |
|---|---|---|
| 1 | Drew Braden Southwest Livingston | 16.5 |
| 2 | TJ Hopkins Mound City | 15.5 |
| 3 | Drake Kinsella Worth County | 14.0 |
| 4 | Ryan Dewhirst Rock Port | 14.0 |
| 5 | Patterson, Caleb North Andrew | 13.5 |
| 6 | Balazs Sturgeon Southwest Livingston | 8.0 |
| 7 | Mason Hawk Worth County | 7.5 |
| 8 | Hughes, Logan North Andrew | 7.0 |
| 9 | Jaden Phelan South Holt/Nodaway-Holt | 6.5 |
| 10 | Zack Oldham Stanberry | 6.0 |
| 11 | Cole Alloway South Holt/Nodaway-Holt | 6.0 |
| 12 | Simon Maize St. Joseph Christian | 6.0 |
| 13 | River McCallon King City | 6.0 |
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