| Rank | Name | Sacks |
|---|---|---|
| 1 | Austin Johnson Southwest Livingston | 19.5 |
| 2 | Jakob Cordell North West Nodaway | 13.0 |
| 3 | Ridge Barron Southwest Livingston | 12.5 |
| 4 | Ben Hart North West Nodaway | 8.0 |
| 5 | Blake Farnan North West Nodaway | 7.5 |
| 6 | Logan Korff Norborne/Hardin-Central | 7.5 |
| 7 | Nali Tattersall South Holt/Nodaway-Holt | 7.5 |
| 8 | Shelby McMillen Stanberry | 6.0 |
| 9 | Colt McIntyre North West Nodaway | 6.0 |
| 10 | Peyton Dodson Southwest Livingston | 5.5 |
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